Assistant Professor & Researcher

Dr. Ali Ghulam

Information Technology Centre
Sindh Agriculture University, Tandojam

Specializing in Human Disease Pathway Network Modeling, Biological Pathway Databases Discovery based on AI, Deep Learning, and Machine Learning. Author of 31+ SCI and 05+ ESCI high-impact research articles.

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Dr. Ali Ghulam
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Dr. Ali Ghulam

About Me

A passionate researcher dedicated to advancing Bioinformatics and AI.

I am Dr. Ghulam Ali, holding a Ph.D. (Doctor of Engineering) in Computer Software and Theory from Shaanxi Normal University, Xi'an, China (2020), awarded under the prestigious CSC Full Scholarship.

Currently serving as an Assistant Professor at the Information Technology Centre, Sindh Agriculture University, Tandojam, my research focuses on human disease pathway network modeling and biological pathway databases discovery powered by Artificial Intelligence.

I have authored extensive work on the Prediction of Pathway Related Protein, Drug and Disease Association based on Complex Networks, AI, Deep Learning, and Machine Learning — publishing over 31 SCI articles and 05 ESCI articles in high-impact journals.

31+
SCI Articles
05+
ESCI Articles
6+
Years Experience
Ph.D.
From China
Personal Details

Father's Name: Haji Khan Rahu
DOB: 02-02-1982
NIC: 45403-0810354-9
Domicile: Sindh (R)
Passport: NU1813541

Research Profiles

ORCID Publons / WoS Google Scholar ResearchGate

Languages

English (Professional)
Urdu (Native)
Sindhi (Native)
Chinese (Basic - BCL-II)

Research & Projects

Current focus on AI, Bioinformatics, and Precision Agriculture.

Present Research Work

Presently working on human protein sequences using machine learning. As the volume and accessibility of Bioinformatics data increases, ML plays a crucial role in diagnosis, structuring, normalizing, and analyzing biological data. Focus areas include precision diagnosis using genomic sequencing, early-stage cancer detection, and advanced cardiac visualization with custom ML/DL models.

Current Research Projects

  • AI-PBTR-Lab: Artificial Intelligence and Precision Biomedicine Technologies Research Lab.
  • Mango Crop Disease: Prediction of Mango Crop of Sindh Based on ML algorithms and IoT.
  • MCDP-MLA: Multiple Crops Disease Prediction Based on Machine Learning Approaches.
  • PDD-UDL: Plants Disease Detection Based on Using Deep Learning.
  • PAAMO-AI: Precision Agriculture and Automation in Mango Orchards using AI (Under Writing).

Research Skills & Tools

Data Science & Bioinformatics
Python Ecosystem NumPy / SciPy Pandas / Matplotlib Seaborn / NetworkX PyRWR / PyGad DNA Sequence Extraction Protein Sequence Extraction Data Visualization
Programming & Software
Python / R / Matlab PyTorch / Spyder MySQL / Oracle / SQL Server PHP / ASP / JSP WordPress / Joomla Linux / Windows Server

Research Publications

Published Impact Factor: 105.259 | 31+ SCI Articles | 05+ ESCI Articles

  • Talpur, F., et al. (2026). Hybrid Particle Swarm Optimization and Ensemble Learning Model of DDoS Attacks Detection. Array.
  • Shafi, H., Ghulam, A., et al. (2026). TRANSWALKCOTNET: A Swin Transformer And Deepwalk-Based Cross-Attention Fusion Framework For Cotton Plant Disease Identification. Genetics and Molecular Research Scopus/HEC-X.
  • Ashraf, M.Z., Kamal, R., Ghulam, A. (2026). AI-Powered Numerical Methods: Transforming Mathematical Problem-Solving. J. of Engineering and Computational Intelligence Review HEC-Y.
  • Ghulam, A., et al. (2026). Bt-Trans Acp: A Binary Tree-Growth Transformer With Hybrid Deep Learning For Anticancer Peptide Prediction. Frontier in Medical and Health Research HEC-Y.
  • Rehman, M., et al. (2026). Integrating Evolutionary and Compositional Features with ML and DL for Robust and Interpretable Druggable Protein Prediction. J. of Computer-Aided Molecular Design (Springer) SCIE, IF: 3.1, HEC-W.
  • Shafi, H., Ghulam, A., et al. (2026). Transformer-Based Cotton Plant Disease Detecting. Advanced Engineering Science Scopus-X.
  • Shafi, H., Ghulam, A., et al. (2026). Heterogeneous Network Framework for Predicting Novel Disease–Plant Associations Using RWR. AgriEngineering SCIE, IF: 3.0, HEC-W.
  • Ghulam, A., et al. (2026). An Explainable Deep Learning Model for Clathrin Protein Prediction. Current Drug Targets SCIE, IF: 2.05, HEC-W.
  • Ghulam, A., et al. (2026). AMP-CapsNet: a multi-view feature fusion approach for antimicrobial peptide prediction. Genomics & Informatics SCI, IF: 1.36, HEC-W.
  • Sikander, R., Ghulam, A., et al. (2026). Accurate Antifreeze Protein Prediction Using a LightGBM-Based Model. Annual Methodological Archive Research Review HEC-Y.

  • Shafi, H., Ghulam, A., et al. (2025). A Comprehensive Review of Complex Network Methods for Cotton Plant Disease Detection. J. of ICT and Robotic Applications.
  • Rehman, M., et al. (2025). Integrating Evolutionary and Compositional Features... J. of Computer-Aided Molecular Design SCI, IF: 3.1.
  • Rehman, M., et al. (2025). ELM-APDPs: An Explainable Ensemble Learning Method... Computer Modeling in Engineering & Sciences SCI, IF: 2.05, HEC-W.
  • Din, A.U., et al. (2025). Towards Sustainable Agri-Food Systems 4.0... Spectrum of Engineering Sciences HEC-Y.
  • Rahu, S., Ghulam, A., et al. (2025). Prediction Of Vesicular Transport Proteins... Spectrum of Engineering Sciences HEC-Y.
  • Abbas, M., et al. (2025). A Deep Learning Framework For Space Weather Prediction... Spectrum of Engineering Sciences HEC-Y.
  • Channar, N.A., et al. (2025). A Review On Edge Ai For Low-Latency Health Monitoring... Spectrum of Engineering Sciences HEC-Y.
  • Sikander, R., et al. (2025). Identification Of Hemagglutinin Using Sequence Information... J. of Medical & Health Sciences Review HEC-Y.
  • Akbar, S.A.A.S., et al. (2025). A Review on Cardiovascular Diseases Risk Prediction... VAWKUM Transactions on Computer Sciences HEC-Y.
  • Israr, M., et al. (2025). Design and Performance Evaluation of Hybrid Solar-Wind Systems... Global Research J. of Natural Science and Tech HEC-Y.
  • Ghulam, A., et al. (2025). An Explainable Phosphorylation Peptide Associated With Sars-Cov-2... Physical Education, Health And Social Sciences HEC-Y.
  • HUSSAIN, Z., et al. (2025). Comparative Evaluation of Elisa, Pcr, And Ns1 Antigen... INSIGHTS-JOURNAL OF HEALTH AND REHABILITATION HEC-Y.
  • Khan, I., et al. (2025). Improved in Silico Identification of Protein‐Protein Interactions... IET Systems Biology SCI, IF: 1.9.
  • Ghulam, A., et al. (2025). StackAHTPs: An explainable antihypertensive peptides identifier... IET Systems Biology SCI, IF: 1.9.
  • Ghulam, A., et al. (2025). An explainable phosphorylation peptide associated with SARS-CoV-2... SOCIAL SCIENCE REVIEW ARCHIVES.

  • Rahu, S., Ghulam, A., et al. (2024). 2DCNN_CLA: Accurate prediction of Clathrin proteins... VAWKUM Transactions HEC-Y.
  • Sikander, R., et al. (2024). An Explainable Identifier of iGHBPs Peptides... Insights-Journal of Health and Rehabilitation HEC-Y.
  • Kausar, F.N., et al. (2024). Effect Of Students'intellectual Ability... Insights-Journal of Life and Social Sciences HEC-Y.
  • Siddiqui, M.A., et al. (2024). Implementation Of NLP In Ehr Systems... Insights-Journal of Health and Rehabilitation HEC-Y.
  • Afzal, M.T., et al. (2024). Telemedicine And Its Effect On Chronic Disease Management... Insights-Journal of Health and Rehabilitation HEC-Y.
  • Rahu, M.U.R., et al. (2024). Accurate Prediction of Monkeypox Disease Cases... SSRN Preprint SCI.
  • Maher, Z.A., et al. (2024). Security Based SCURM Process (SUBSCRUM)... VFAST Transactions on Software Engineering HEC-Y.
  • Arif, M., et al. (2024). StackDPPred: Multiclass prediction of defensin peptides... Methods SCI, IF: 4.02, HEC-W.
  • Arif, M., et al. (2024). DPI_CDF: druggable protein identifier using cascade deep forest. BMC bioinformatics SCI, IF: 3.09, HEC-W.
  • Talpur, F., et al. (2024). ML-Based Detection of DDoS Attacks Using Evolutionary Algorithms. Sensors HEC-W.

  • Ghulam, A., Rehman, M. (2024/23). Assessment of Performance of ML for Monkey Pox... JIICET.
  • Memon, M., et al. (2023). AiDHealth: An AI-enabled Digital Health Framework...
  • Sikander, R., Ghulam, A., et al. (2023). Identification of cancerlectin proteins... Mehran University Research J. WoS, HEC-X.
  • Magsi, A.H., et al. (2023). A Content Poisoning Attack Detection... Sustainability SCI, IF: 3.889, HEC-W.
  • Magsi, A.H., et al. (2023). A machine learning-based attacks detection... Computers, Materials and Continua SCI, IF: 3.9, HEC-W.
  • Hassan, J., et al. (2023). A Survey on Blockchain-based Intrusion Detection... VAWKUM Transactions HEC-Y.
  • Ghulam, A., et al. (2023). DeepImmuno-PSSM: Identification of Immunoglobulin... VFAST Transactions HEC-Y.
  • Qureshi, R., et al. (2023). A Survey on Security Issues and Attacks of Fog Computing. VFAST Transactions HEC-Y.

  • 2022: Swati, Z.N.K., Ghulam, A., et al. XGboost-Ampy... VAWKUM HEC-Y.
  • 2022: Sikander, R., Ghulam, A., et al. AOPs-XGBoost... VAWKUM HEC-Y.
  • 2022: Hassan, J., et al. Disease Identification using Deep Learning in Agriculture... VFAST HEC-Y.
  • 2022: Rahu, S., Ghulam, A., et al. Ubi-Xgb: Identification of Ubiquitin Proteins... J. of Mountain Area Research HEC-Y.
  • 2022: Ghulam, A., et al. Identifying Molecular Functions of Dynein Motor Proteins... J. of Mountain Area Research HEC-Y.
  • 2022: Talpur, D.B., Ghulam, A., et al. Accurate prediction of Snare Protein... Bioscience Research ESCI, HEC-Y.
  • 2022: Sikander, R., et al. Identification of the ubiquitin–proteasome pathway... Frontiers in Genetics SCI, IF: 4.772, HEC-W.
  • 2022: Chanihoon, G.Q., et al. Selenium and Mercury Concentrations... J. of Trace Elements in Medicine SCI, IF: 3.995, HEC-W.
  • 2022: Ghulam, A., et al. ACP-2DCNN: Deep learning-based model... Chemometrics and Intelligent Lab Systems SCI, IF: 4.175, HEC-W.
  • 2022: Sikander, R., Ghulam, A., et al. XGB-DrugPred... Scientific Reports SCI, IF: 4.996, HEC-W.
  • 2022: Ghulam, A., et al. Human drug-pathway association prediction... Computational Biology and Chemistry SCI, IF: 3.737, HEC-Y.
  • 2021: Ali, F., Ghulam, A., et al. Deep-PCL... Chemometrics and Intelligent Lab Systems SCI, IF: 4.175, HEC-W.
  • 2021: Sikander, R., et al. Identification of Enzymes-specific Protein Domain... Frontiers in Genetics SCI, IF: 4.772, HEC-W.
  • 2021: Ali, F., et al. AFP-CMBPred... Computers in Biology and Medicine SCI, IF: 6.698, HEC-W.
  • 2020: Ghulam, A., Lei, X., et al. Identification of Pathway-Specific Protein Domain... IEEE Access SCI, IF: 3.476, HEC-W.
  • 2020: Ghulam, A., Lei, X., et al. Disease-pathway Association Prediction... IEEE Access SCI, IF: 3.476, HEC-W.
  • 2020: Ghulam, A., et al. Comprehensive Analysis of Features... Current Bioinformatics SCI, IF: 4.850, HEC-X.
  • 2019: Ghulam, A., et al. Pathway-specific Protein Domains (PSPD)... Algorithms for Molecular Biology SCI, IF: 1.706.
  • 2018: Maher, Z., et al. A methodology for modeling and analysis of secure systems... IEEE ICCCE.
  • 2017: Ghulam, A., et al. On-Page Search Engine Optimization (SEO)... IJRASET.

Conference Publications

  • IBRAS 2026: CAPSDPP: A Capsule-Inspired Deep Learning Framework... (Karachi)
  • EMERGING TRENDS 2026: Predicting DNA-Binding Proteins with Hybrid Architecture...
  • ICETAS 2023 (IEEE): Feature Based Comparative Analysis of Traditional IDS and SDN...
  • KHI-HTC 2024 (IEEE): Prediction of Monkeypox Disease based on ML Methods.
  • KHI-HTC 2024 (IEEE): Identifying DNA-Binding proteins using local features...
  • KHI-HTC 2024 (IEEE): Classification of antihypertensive peptides (AHTP)...
  • KHI-HTC 2024 (IEEE): A Comprehensive Survey of SDN and its Security Threats.
  • Emerging Scientist 2024: A Novel Machine Learning Computational Identification of GHBPs...

Supervision & Evaluations

Guiding the next generation of researchers.

Ph.D. Supervision

  • Main: Hina Shafi (PhD-2K23-IT-02) - "Predicting cotton plant disease associations using complex networks"
  • Main: Nazir Ahmed Marri (Ph.D. 2k23-IT-06)
  • Co-Sup: Syed Akbar Ali Shah (Univ. of Sindh)
  • Co-Sup: Saima Shaik (PhD-2K23-IT-08) - "Evolutionary framework for software defect prediction..."

MS / MSAI Supervision

  • Aarifa Khatoon: "Identification of various crop disease detection based on hybrid features..."
  • Tarique Ali: "Prediction of chronic diseases utilizing two heterogeneous pipelines..."
  • Hazrat Noor: "An explainable approach for detecting of DDOS attacks..."
  • Co-Sup: Rana Ehtsham Ul Haq - "Machine learning-based traffic recognition..."
  • Co-Sup: Abdul Waheed - "Prediction of student performance using decision support system"

Thesis Evaluations (External Examiner)

Ph.D. Evaluations
  • Dr. A.H.S. Bukhari (PG Centre of ICT, Univ. of Sindh)
  • Institute of Mathematics & Computer Science (Univ. of Sindh)
MS / M.Phil Evaluations (KIU Gilgit - Jan 2026)
  • Kumail Abbas: "Interpretable Machine Learning: Bridging the Gap..."
  • Rehmat Ali: "Enhancing Aspect Based Text Generation using Deep Learning"
  • Rashid ud Din: "A Comparison of the Data Traffic... via Edge Computing"
  • Zaheer Abbas: "Cockpit and White Noise Cancellation Headphones"
  • Syed Saqib Hussain: "Hybrid Cnn-Transformer Model For Alzheimer's..."
  • Junaid Abbas Qazalbash: "Improving Cyber Defense Decision Making..."

Peer Journal Reviewer & Advisory Board

Frontiers in Genetics Informatics in Medicine Unlocked RADS J. of Computer Science Computational Intelligence and Neuroscience CMC-Computers, Materials & Continua Journal of Cheminformatics Scientific Reports The Protein Journal (Springer) BMC Infectious Diseases Discover Applied Sciences Current Protein & Peptide Science Current Drug Targets Advisory Board: AxisJHRS

Professional Experience

A journey of academic and technical excellence.

April 2023 - Present

Assistant Professor

Information Technology Centre, Sindh Agriculture University, Tandojam.

Teaching Bioinformatics, AI, Deep Learning, Machine Learning, and Computational Professional Practices. SAU-UMS Team Lead.

Nov 2022 - April 2023

Lecturer

Information Technology Centre, SAU Tandojam.

Teaching specialization in Bioinformatics, AI, Deep Learning, and Machine Learning.

July 2007 - Oct 2022

Webmaster / Web Developer

Sindh Agriculture University Tandojam.

Website Development, Graphics Designing, WordPress, Joomla, SEO, PHP, MySQL, Apache Tomcat, IIS Server.

2008 - Present

Senior Web Developer / Team Lead

Ora-Tech System Karachi.

Designed and developed web sites for 30 Govt Departments and 23 Districts of Sindh. Portal administration and team leadership.

May 2005 - May 2006

Assistant System Developer

Alpha Insurance Company Ltd, Karachi.

Visual Studio.Net 2003, Oracle 9i, Crystal Report 10. Under Writing System, Motor/Marine/Fire Departments policies.

Education & Certifications

Academic background and continuous learning.

Academic Degrees

  • Ph.D. (Doctor of Engineering) 2017 - 2020
    Shaanxi Normal University, Xi'an, China. (CSC Full Scholarship)
    Thesis: "Prediction of Pathway Related Protein, Drug and Disease Association Based on Complex Network and Deep Learning"
  • M.Phil (Computer Science)
    Institute of Computer Science, University of Sindh, Jamshoro. (Specialization: SEO)
  • Bachelor of Computer Science (BCS-HONS) 2005
    Institute of Computer Science, University of Sindh, Jamshoro.
  • F. Sc. (Pre-Medical) 1999
    Govt Sarwari Islamia Degree College Halla, Sindh.
  • Matriculation 1997
    Govt. High School Sabu Rahu, Distt. Nawabshah, Sindh.

Diplomas & Certifications

  • CIT: Computer Academy, Hyderabad (2002)
  • DIT: AI Soft, Hyderabad (2002-2003)
  • WordPress Test: Certified Developer (Score: 2.75, 67%)
  • Joomla 1.5 Test: Certified (Score: 2.50, 24%)
  • SQL Server & Azure: Microsoft Data Platform Training (HEC, 2016)
  • IT Management: TESP, HEC, IBA Karachi (2015)
  • Basic Chinese Language (BCL-II): Confucius Institute, Karachi (2014-2015)

Courses Taught

Artificial Intelligence
ITC-606
Advanced AI
AI-717
Foundational Math & AI
AI-720
Bioinformatics
ITC-501
Graph Theory
CS-503
Computational Practices
ITC-604
Fundamental Programming
CS-303
OOP (CS & SE)
Batches

Honors & Awards

  • CSC Full Scholarship (2017-2020)
    China Govt Scholarship Council for Doctoral Degree.
  • All Pakistan Website Competition
    3rd Position, Presidential Iqbal Awards.
  • Award of Prime Minister of Pakistan
    Shield for 3rd position in 2nd Multimedia Website Dev Competition, Iqbal Academy Lahore.

Focal Person Assignments

  • SAU-UMS Team Lead (University Management System) 2025-2026
  • Focal Person (DLSEI) HEC Pakistan (2025-2026)
  • Focal Person (Office 365) HEC
  • Coursera License via HEC's portal

Committees & Memberships

  • UI GreenMetric World University Ranking 2026
  • IT Team, Undergraduate Admission 2025-26
  • Technical Program Committee (ICDDSC-2025)
  • Chair Publicity / Social Media
  • University Admissions Entry Test Management
  • Final Year Project Display Committee
  • SAU Official Website Dev Committee

Get In Touch

Feel free to reach out for collaborations, research discussions, or academic inquiries.

Phone
0300-3219350
Official Email
garahu@sau.edu.pk
Personal Email
ali.rahu@gmail.com
Office Address
ITC, SAU Tandojam
Sindh, Pakistan

Connect on Research Platforms

ORCID
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Google Scholar
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Publons / WoS
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ResearchGate
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Passport No
NU1813541
NIC
45403-0810354-9

References

Dr. Mir Sajjad Hussain Talpur
Professor

Information Technology Centre
SAU, Tandojam

Dr. Zulfikar Ahmed Maher
Assistant Professor

Information Technology Centre
SAU, Tandojam